Discoid Lupus Erythematosus (DLE): primarily affects the skin, particularly around the face, ears, and nose. Dogs with DLE typically develop skin lesions, ulcers, crusting, and depigmentation in these areas. An early sign is pigment loss in the nose progressing to cracking & ulcerations. DLE can also affect lips, ears and feet. Sun exposure worsens the condition. Unlike SLE, DLE does not involve systemic inflammation or organ damage. It is considered less severe but can still cause discomfort and cosmetic changes in affected dogs.
Nutrition: Feeding a low carbohydrate, novel protein diet can support their immune system and overall health. Incorporating anti-inflammatory foods such as omega-3 fatty acids (found in fish oil) and antioxidants (found in fruits and vegetables) may help reduce inflammation associated with lupus. Avoiding high glycemic foods (e.g. dog biscuits, treats made with sugar or molasses) can also reduce overall inflammation that triggers flare-ups.
Supplements: Certain supplements may benefit dogs with lupus by supporting immune function and reducing inflammation. These may include omega-3 fatty acids, vitamin E, plant sterols, and probiotics. However, it's essential to consult with a veterinarian before adding supplements to ensure they are safe and appropriate for the dog's condition.
Stress Reduction: Stress can exacerbate symptoms of autoimmune diseases like lupus. Providing a calm and stable environment for the dog, minimizing stressors, and incorporating relaxation techniques such as massage, acupuncture, or aromatherapy can help reduce stress and promote overall well-being. CBD oil can also be helpful for stressed pets.
Immune Modulation: Plant sterols have been shown to modulate the immune response by influencing the production and activity of certain immune cells and cytokines. In dogs with lupus, whose immune systems are overactive and may be attacking healthy tissues, plant sterols could help restore balance and reduce autoimmune reactions.
Anti-inflammatory Effects: Inflammation is a key feature of lupus, contributing to tissue damage and symptoms such as joint pain and skin lesions. Plant sterols have demonstrated anti-inflammatory properties which could help alleviate inflammation associated with lupus and reduce the severity of symptoms.
Cardiovascular Support: Lupus can increase the risk of cardiovascular complications in dogs, including heart disease and hypertension. Plant sterols have been shown to lower cholesterol levels and support cardiovascular health in humans, which may be beneficial for dogs with lupus, especially if they have concurrent cardiovascular issues.
Antioxidant Activity: Some plant sterols possess antioxidant properties, helping to neutralize harmful free radicals and reduce oxidative stress. This could be particularly beneficial for dogs with lupus, as oxidative stress is believed to contribute to tissue damage and inflammation in autoimmune diseases.
Gut Health: Plant sterols may also support gut health by promoting the growth of beneficial gut bacteria and maintaining the integrity of the intestinal barrier. A healthy gut microbiome is essential for proper immune function and may help modulate the immune response in dogs with lupus. Probiotics can also help with gut health.
